Ask a Psychiatrist
Is it safe to take antidepressants while pregnant?
Often, yes. And the half of the math the warning labels skip is that untreated depression during pregnancy carries real risks too, for both of you. Sertraline (Zoloft) has the deepest pregnancy safety record; the decision weighs your history, severity, and trimester, with ACOG's guidance as the backdrop.
Medically reviewed by Dr. Akinwande Akintola, MD — Sun Jul 19 2026
Often, yes. And the half of the math the warning labels skip is that untreated depression during pregnancy carries real risks too, for both of you. Sertraline (Zoloft) has the deepest pregnancy safety record; the decision weighs your history, severity, and trimester, with ACOG's guidance as the backdrop.
The one thing we push back on hard: stopping cold the day the test turns positive. Relapse mid-pregnancy is common and rough. This exact conversation, with numbers instead of fear, is what a perinatal consult is for.
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